Rivaroxaban CAS 366789-02-8 Purity >99.5% (HPLC) Factory API High Quality

Short Description:

Chemical Name: Rivaroxaban

CAS: 366789-02-8

Purity: >99.5% (HPLC)

Appearance: White or Almost White Powder

API High Quality, Commercial Production

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

Description:

Manufacturer Supply Rivaroxaban Related Intermediates:
(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0
4-(4-Aminophenyl)morpholin-3-one CAS 438056-69-0
Rivaroxaban Intermediate CAS 446292-07-5
5-Chlorothiophene-2-Carboxylic Acid CAS 24065-33-6
5-Chlorothiophene-2-Carbonyl Chloride CAS 42518-98-9
Rivaroxaban API CAS 366789-02-8

366789-02-8 - Chemical Properties:

Chemical Name	Rivaroxaban
Synonyms	(S)-Rivaroxaban; (S)-5-Chloro-N-[[2-oxo-3-[4-(3-oxomorpholino)phenyl]oxazolidin-5-yl]methyl]thiophene-2-carboxamide; BAY 59-7939; Rivaroxaban Isomer
CAS Number	366789-02-8
Stock Status	In Stock, Production Scale Up to Tons
Molecular Formula	C19H18ClN3O5S
Molecular Weight	435.88
Melting Point	228.0~229.0℃
Density	1.460±0.06 g/cm3
Sensitive	Air Sensitive, Heat Sensitive
Solubility in Water	Insoluble in Water
Solubility	Soluble in Dimethylformamide, Very Slightly Soluble in Ethanol
COA & MSDS	Available
Place of Origin	Shanghai, China
Brand	Ruifu Chemical

366789-02-8 - Specifications:

Item	Specifications
Appearance	White or Almost White Powder
Identification A	The infrared absorption of Rivaroxaban corresponds to reference standards
Identification B	The retention time of the main peak of the sample solution corresponds to that of the system suitability solution ,as obtained in the enantiomeric purity.
Enantiomeric Purity	RVX RC01: ≤0.15%
Moisture (K.F)	≤0.50%
Sulphated Ash	≤0.10%
Heavy Metals	≤20ppm
Acetic Acid	≤5000ppm
Related Substances (HPLC)
RVX RC02	≤0.15%
RVX RC03	≤0.15%
RVX RC04	≤0.15%
RVX RC05	≤0.15%
RVX RC06	≤0.15%
RVX RC07	≤0.15%
RVX RC08	≤0.15%
Any Other Individual Impurity	≤0.10%
Total Impurities	<0.50%
Residual Solvents (GC)
Ethanol	≤5000ppm
Toluene	≤890ppm
Triethylamine	≤320ppm
Purity / Analysis Method	>99.5% (HPLC) (on anhydrous basis)
Test Standard	Enterprise Standard
Usage	API; Antithrombotic Drug; FXa Inhibitor

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

FAQ:

366789-02-8 - Application:

Rivaroxaban (CAS: 366789-02-8) (Xarelto, Bayer) is an oral anticoagulant. It is an orally active direct factor Xa inhibitor. Rivaroxaban is indicated for the 'treatment of deep vein thrombosis and pulmonary embolism, and prevention of recurrent deep vein thrombosis and pulmonary embolism in adults'. For the initial treatment of acute pulmonary embolism, the recommended dosage of rivaroxaban is 15 mg twice daily for the first 21 days followed by 20 mg once daily for continued treatment and prevention of recurrent venous thromboembolism. Non-Valvular Atrial Fibrillation (NVAF) to prevent stroke & systemic embolism. Acute VTE treatment & prevention of recurrent VTE [for deep vein thrombosis (DVT) and pulmonary embolism (PE)]. Prevention of venous thromboembolic events (VTE) in elective total hip or knee replacement surgery (THR, TKR).